BTNL2 gene polymorphism associations with susceptibility and phenotype expression in sarcoidosis
نویسندگان
چکیده
منابع مشابه
BTNL2 Gene Polymorphism and Sarcoidosis Susceptibility: A Meta-Analysis
BACKGROUND Butyrophilin-like 2 (BTNL2) rs2076530 gene polymorphism has been implicated in susceptibility to sarcoidosis. However, results from previous studies are not consistent. To assess the association of BTNL2 polymorphism and sarcoidosis susceptibility, a meta-analysis was performed. METHODS PubMed, Embase were searched for eligible case-control studies. Data were extracted and pooled o...
متن کاملBTNL2 gene variant and sarcoidosis.
is a safe test when performed in experienced centres. Indeed, a review of .6500 ITTs reported that only seven patients (0.1%) experienced an adverse event, all of which reversed following intravenous glucose. To our knowledge, only two studies have used the ITT to investigate the HPA axis in asthmatic children treated with inhaled fluticasone. The first reported an inadequate response to insuli...
متن کاملThe BTNL2 G16071A gene polymorphism increases granulomatous disease susceptibility
OBJECTIVE The butyrophilin-like 2 (BTNL2) G16071A gene polymorphism has been implicated in the susceptibility to granulomatous diseases, but the results were inconclusive. The objective of the current study was to precisely explore the relationship between BTNL2 G16071A gene polymorphism and granulomatous disease susceptibility by the meta-analysis including false-positive report probability (F...
متن کاملMajor histocompatibility complex class II and BTNL2 associations in sarcoidosis.
Infect Dis 2009; 9: 162–172. 4 Li T, Chiang JY. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4a and coactivators, and suppression of small heterodimer partner gene expression. Drug Metab Dispos 2006; 34: 756–764. 5 Handschin C, Meyer UA. Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. Arch Biochem ...
متن کاملLack of correlation of BTNL2 polymorphism and cancer risk in sarcoidosis. BTNL2 and cancer risk in sarcoidosis.
BACKGROUND Sarcoidosis is a polygenic immune disorder disease with predominant manifestations in the lung. BTNL2 gene polymorphisms were previously linked to susceptibility to sarcoidosis. Relationships between sarcoidosis and cancers have been suspected for a long time but little evidence has been reported until now, and recent works show a link between butyrophilin family proteins and anti tu...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2012
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2012.08.009